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General Guidelines for Female Athletes Dose Range : 1020 micrograms (mcg) per day Frequency : 5 days on, 2 days off (or every other day) Timing : Best: Immediately post-workout with carbs and protein Alternate: First thing in the morning, not fasted Cycle Length : 4 to 6 weeks per cycle Off-Cycle : Equal or greater time off (e.g., 46 weeks) This keeps IGF-1 levels elevated without desensitizing receptors or risking long-term metabolic fatigue

Notably, IGF-1 LR3 enhances muscle sensitivity to insulin, thereby promoting glucose uptake and utilization while simultaneously reducing fat storage

Curr Opin Rheumatol (2008) 20(6):7208

Erastin was reported to cause cancer cells to perish via undetermined mechanisms in 2003 [23]

Antioxidants (Basel) 11(5):989